We are going through some challenges as Coronavirus spreads all over the world.It makes sense for us to be braced and have knowledge on best approaches to help our body fight the virus, in case it will be needed. We put together several informations and research content about supplements that can help fighting virus infections for you.
What this is:
What this is: Glycyrrhizinate is the major active component of licorice root extract, an ancient medicinal plant sometimes also used as alternative cancer treatment. Licorice can be found as a food supplement at shops on-line.
What is the potential:
- Has been employed against coughs and colds for long time in traditional Chinese medicine as well as to settle disturbed digestion and has anti-inflammatory activity
- It is well recognised as an extract that has antiviral activity (Ref.1, Ref.2, Ref.3 )
- One German study reports in 2003: “Of all the compounds, glycyrrhizin was the most active in inhibiting replication of the SARS-associated virus. Our findings suggest that glycyrrhizin should be assessed for treatment of SARS” (Ref.)
- Professor Hong Ding of Wuhan University has proposed a combination of diammonium glycyrrhizinate and vitamin C as a COVID-19 therapy and a clinical trial is running on this now (Ref.1, Ref.2)
How to take: The clinical trials gives Diammonium Glycyrrhizinate Enteric-coated Capsules (oral, 150mg, Tid), Vitamin C tablets (oral, 0.5g, QD). That means 450mg Glycyrrhizinate/day and 2g Vitamin C/day. Glycyrrhizinate capsules are available in China only. As an alternative to that, I would use licorice root extract supplements since they contain high amount of Glycyrrhizinate. Glycyrrhizin, glycyrrhizic acid, and glycyrrhizinate amount to 10% to 25% of the root extract (Ref.). Assuming 10% Glycyrrhizinate, in order to achive the dose used in the clinical trial we would need to use about 5g Licorice root extract/day. This seems safe, given that Licorice root has been used in daily doses from 760 mg to 15 g for ulcer and gastritis (Ref.).