We are going through some challenges as Coronavirus spreads all over the world.It makes sense for us to be braced and have knowledge on best approaches to help our body fight the virus, in case it will be needed. We put together several informations and research content about supplements that can help fighting virus infections for you.
There is an an additional strategy for the use of cancer drugs in treatment and prevention of viral infections. This strategy especially puts focus on the Coronavirus (2019-nCoV).
Between cancer cells and virus-infected cells, there is a remarkable similarity, in that both go through a metabolic shift from oxidative phosphorylation to glycolysis.This process is also known as “Warburg effect”.
The Warburg effect, lowers intracellular pH (pHi) due to lactic acid accumulation. It results in both cell types have to work heavily in exporting lactic acid to maintain the right pHi.
A correct pHi is essential for keeping an increased cell cycle rate (cancer cells) and for assembling new viruses (virus-infected cells).
The other feature both cell types have in common, is that they rely on fatty acid synthesis, to boost lipid production for proliferation (cancer) or for envelope assembly (virus).
Coronaviruses are put together ouf RNA and viral proteins in the endoplasmic reticulum Golgi intermediate compartment.
Viral proteins are extremely sensitive to changes intracellular ion composition, while they assemble, that’s a distinctive mechanism and it can be targetedwith selective Ionophore drugs. The K/Na/H+ ionophore Monensin, which develops the right balance of ions, can cause defective changes of essential coronavirus proteins, for example (e.g. glycoproteins E1 and E2, Ref.).
Moreover, one of the most critical parameters for the assembly of different types of viruses is intracellular pH, and it is possible that by lowering pHi with specific drugs, one can effectively interfere with virus amplification cycles. The following forum contains a list of many drugs that are capable of lowering pHi: (https://www.cancertreatmentsresearch.com/ph-cancer-a-top-treatment-strategy/).
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